Combine Orange Skunk with Jack's Cleaner and Space Queen, and you get Agent Orange – no, not the Vietnam-era pesticide, but rather the medical marijuana strain. Agent Orange also known as “Agent O,” a sativa, produces an uplifting cerebral high ideal for depression, anxiety, and migraines. It can be useful in treating minor aches and pains, but it isn't recommended for treatment of chronic pain. The high starts to descend after just half an hour, making this a good strain for daytime activities and house chores. Agent Orange smells like citrus, naturally, and it tastes like sweet and spicy oranges, while the bud has a deep purple appearance. There are few adverse effects, though dry mouth is possible.