Bio Kratom has a strong effect on your anxiety, mood and energy levels. It lowers your anxiety level, while the feeling has been described as happy, strong, and active, with a strong desire to do work. The mind is described as calm. Thai workers use it to get through a hard day of work. Effects come on within five to ten minutes after use, and can last for several hours. Most people describe the effects as stimulating and euphoric at lower doses, becoming sedative at higher doses. This is probably explained by the fact that mitragynine stimulates the delta opioid receptors when used in small quantities, but tends to increasingly stimulate mu opioid receptors when used in larger quantities. These are the same receptors that are stimulated when using opiate drugs. Maeng Da: (Thai) Maeng Da kratom is translated as ‘pimp grade’ kratom and originates from Thailand. It is the strongest kratom strain available today. According to users, Maeng Da is less euphoric than other strains, but it’s praised for its energizing effects. Critics say it’s more jittery than other Premium Thai strains, and argue it doesn’t last as long. The active dose is 1-2 grams. High quality Maeng Da is very green in color.